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Codeine After Surgery Could Endanger Certain Kids: Study

WEDNESDAY, April 11 (HealthDay News) -- Concerns about codeine safety have gained traction in the wake of the postoperative experience of four children who all carried a rare genetic mutation. A new study describes what happened to three of the patients, while a similar case came to light in 2009.

In certain very rare genetic cases, the common painkiller codeine can be lethal. The gene mutation causes the body to metabolize codeine into morphine at levels 50 percent to 70 percent higher than normal. Among such patients, an otherwise standard amount of codeine can unpredictably turn into a toxic overdose.

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Higher Altitude May Lead to Lower Weight, Study Contends

THURSDAY, May 7, 2015 (HealthDay News) -- People who live at higher altitudes are less likely to become overweight or obese, a new study suggests.

The research included more than 9,300 Spanish university graduates who were not overweight or obese at the start of the study. They were divided into three groups based on their homes' altitude: below 407 feet (low); 407 to 1496 feet (medium); and above 1496 feet (high).

Over a median follow-up of 8.5 years, nearly 2,100 of the participants became overweight or obese. After accounting for other factors, such as diet and physical activity, the researchers concluded that study participants who lived at high altitudes were 13 percent less likely to become overweight or obese than those who lived at low altitudes.

However, while the study did find an association between altitude and weight, it wasn't designed to show that living at a certain altitude can actually cause changes in weight.

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